Typical vial
5 mg
Common dose
1 mg
Frequency
1×/week
Half-life
7d
Calculate Semaglutide reconstitution
Open the free calculator pre-filled with Semaglutide values — no account needed.
Dosing & Protocol Overview
Research Notes
GLP-1 agonist studied at weekly intervals; research protocols often escalate monthly.
How Reconstitution Works
Reconstitution is the process of mixing a lyophilized (freeze-dried) peptide powder with bacteriostatic water to create an injectable solution. The concentration depends on how much BAC water you add to the vial.
For a 5 mg vial of Semaglutide, the calculator works out the mg/ml concentration based on your BAC water volume, then converts your target dose (1 mg) into the exact number of units to draw on an insulin syringe.
Try it now — pre-filled for SemaglutideTrack Your Semaglutide Protocol
Once you've calculated your reconstitution, ReconDose lets you log every injection, build a dosing schedule, track side effects, and record biomarkers — all in one place. Create a free account to get started.
Research & References
The following publicly available studies are provided for research and educational purposes only. They are not medical advice. Click through to read the original publications.
Frias JP, et al. · New England Journal of Medicine · 2021
Phase 3 trial comparing tirzepatide vs semaglutide (1 mg) over 40 weeks. Semaglutide achieved -1.86% HbA1c reduction. Established the comparative efficacy profile between these two GLP-1 receptor agonists.
Karagiannis T, et al. · Diabetologia · 2024· CC-BY
Network meta-analysis of 28 trials with 23,622 participants. Semaglutide 2.0 mg achieved -1.59% HbA1c reduction and semaglutide 1.0 mg achieved -1.39%. Provides comparative efficacy data across GLP-1 receptor agonist doses.
Have a study we should add? Let us know. See our research hub for more studies and the Khavinson peptide bioregulator collection.